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Gopalan Vivek PhD Student Department of
Biochemistry & Bioinformatics Centre 10 Phone (work) :
65-68744459 (home)
65-62708024 Email: vivek@bic.nus.edu.sg |
EDUCATION
June 2001-present
Ph.D in Bioinformatics
at
June 1993 – June 1997
Completed B.Tech (Industrial Biotechnology) at
CGPA – 8.5 / 10; 4th
rank holder.
WORK EXPERIENCE
June 1997 - Dec 1998
Research Fellow in Vittal Mallya Scientific Research
Foundation (United Breweries),
Dec 1998 – May 2001
Research Scientist-I in Vittal
Mallya Scientific Research Foundation,
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Development of an adaptive neuro-fuzzy control system using MATLAB neural network,
fuzzy logic and simulink toolboxes for automation of
beer fermentation.
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Development of thermo-tolerant
strain from a high-alcohol and osmo-tolerant Yeast
strain.
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Estimation of experimental
parameters for optimal extra neutral alcohol production using an alcohol tolerant, osmo-tolerant
and flocculating yeast strain in industrial
fermentors.
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Scale up studies on solid substrate
fermentation and down stream processing of Xylanase
enzyme.
·
Process Design, scale up,
cost estimation and installation of pilot plant and production unit (2000 kgs per month) for purified Hydroxycitric
acid and its salt forms from Garcinia fruit
rind.
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Scale up studies on purification of Azadirachtin from Neem seeds.
Bioinformatics
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Set-up and usage of stand-alone
BLAST2 & Fasta3
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EMBOSS, VectorNTI,
HMMER2.2, PRATT
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ClustalW & ClustalX, PHYLIP, Rasmol/Chime
scripting
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Sybyl, Insight, SPSS (statistics)
Computer Knowledge
Languages: C, Pascal, Javascript, JAVA and
PERL
Packages : Matlab,
Simulink, MS Office, Apache web servers.
Databases : MySQL, MS-Access
Operating
Systems : Unix( Linus, Irix,
Solaris), Windows 98/2000.
Biotechnology
Strong
skills in protein purification, expression, enzyme assays, DNA and RNA
isolation, hybridization techiques, molecular
cloning, restriction analysis, shake-flask & benchscale
fermentation and various microbiological techniques.
CONTRIBUTIONS TO RESEARCH
Publications
Gopalan Vivek, Tin Wee Tan and Shoba
Ranganathan. XdomView:
Protein Domain and Exon Position Visualization, 2002,
Bioinformatics [In Press]
Posters
10th International Conference on
Intelligent Systems for Molecular Biology,
2nd NUS-Sydney International Bilateral Symposium on
AWARDS & ACHIEVEMENTS
·
Awarded
merit scholarship for pursuing Master in Bioinformatics at National University
of Singapore based on merit.
DETAILS OF M.Sc PROJECT
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Title |
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Analyses of protein domains and
genomic elements using bioinformatics approach. |
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Duration |
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June 2001 - |
A web-based graphical tool that maps and visualizes domain
regions in the input PDB chain and intron
positions/phases of its homologous proteins to the protein 3D structure has
been developed. It involved extensive perl
programming and MySQL database concepts.
DETAILS OF B. TECH
PROJECT
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Title |
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Computational Framework for the Flux Balance
Analysis |
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Duration |
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Jan 1997- May
1997 (6 months) |
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Development of
a comprehensive framework for the catabolic and the biosynthetic pathways in E.coli
containing almost 155 fluxes with 119 metabolites was generated for
optimizing the growth using glucose and acetate as feed using linear
optimization techniques. The project involved programming in MATLAB,
large-scale matrix handling, graphical visualization of metabolic fluxes and
linear optimization. Kindly check
the presentation at http://surya.bic.nus.edu.sg/vivek/mfa.ppt
for more details. |
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PERSONAL DETAILS
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Nationality |
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Address |
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Permanent
address |
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Temporary/Contact
Address |
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Ponnappa Nadar Nagar Nagercoil 629004 Tamil Nadu Tele: 91-4652-260122 |
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#20-145, Block 2 Tele (off): 65-6874-4459 Tele (res): 65-6270-8024 |
HOBBIES
Playing
Cricket, football and Volleyball.
REFERENCES
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Dr. Shoba Ranganathan Associate Professor Department of Biochemistry URL: http://surya.bic.nus.edu.sg/shoba Email: shoba@bic.nus.edu.sg
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Dr. Tan Tin Wee Associate Professor Department of Biochemistry URL: http://olympus.bic.nus.edu.sg/~tinwee/
Email: tinwee@bic.nus.edu.sg
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